logo An introduction to dermatological therapeutics

Introduction to dermatology

Therapeutics key points test

When selecting a topical medication, the most important factors to consider are the active ingredient and the: *! Base * Colour * Trade name * Preservative Explanation: Therapeutic effect of topical medications depends on the nature of the base, the site to which it is applied and the specific skin condition. Scalp dermatoses should be treated with a: * Paste * Powder *! Lotion * Ointment Explanation: Most scalps are covered with hair, so it is inconvenient and messy to use ointments and pastes. Lotions and solutions are more practical. Blisters are dried up by: *! Wetting them * Drying them Explanation: Blisters ('wet' skin) should be dried up using 'wet' astringent applications Ointments are used for * Wet skin conditions *! Dry skin conditions Explanation: Thicker ointments are used to moisturizer dry skin conditions Topical medications may result in contact allergy, which is most often due to its: * Dye * Container * Vehicle *! Preservative Explanation: Numerous potential allergens are found in topical medications including dye, vehicles, leached allergens from the container) but preservatives and fragrances are the most common to cause contact dermatitis Potent topical steroids are used for short courses for flare-ups and should be avoided where the skin is: *! Thin * Thick Explanation: Potent topical steroids should not be applied for more than a few days where the skin is thin, because corticosteroids cause dermal atrophy. When topical steroids are required long term it is usually best to choose: *! A mild preparation such as hydrocortisone acetate * A potent preparation such as clobetasol propionate Explanation: It is safer to use mild preparations long term. However, in severe skin conditions it may also be necessary to use short courses of more potent products or intermittent pulses, for example at weekends. The development of bacterial resistance is: * More likely if oral antibiotics are used than if topical antibiotics are used *! More likely if topical antibiotics are used than if oral antibiotics are used Explanation: Topical antibiotics are prone to result in bacterial resistance, possibly because they are used in too low concentration and intermittently allowing relatively resistant strains to proliferate