Which of the following statements are true?
# Dry skin results from lack of water in the basal layer
#! Occlusive emollients provide a layer of oil on the skin surface to slow water loss
#! Humectants increase the water holding capacity of the stratum corneum
#! Humectants include urea and lactic acid
Explanation: Emollients relieve dry skin, which is due to lack of water in the stratum corneum. Oil seals the water in. Humectants such as urea and alpha hydroxy acids such as lactic and glycolic acids allow more water to be retained.
Adverse reactions to emollients include:
#! Contact dermatitis
#! Perioral dermatitis.
Explanation: Emollients may result in stinging and contact urticaria due to fragrances or other components, contact irritant dermatitis and contact allergic dermatitis. Their occlusive nature may also provoke follicular facial rashes such as acne, rosacea and perioral dermatitis.
Arrange the following topical steroids in order of potency, with the most potent first.
Mix and match [table]:
Clobetasol propionate: 1 (most potent)
Betamethasone valerate: 2
Clobetasone buyrate: 3
Hydrocortisone acetate: 4 (least potent)
Explanation: Become familiar with at least one topical steroid from each class of potency; fully funded options are available for each class.
Select a suitable topical steroid to apply to moderately severe eczema for up to two weeks for each body site:
Mix and match [table]
Sole of foot : Ultrapotent (Class 1)
Arm : Potent (Class 2)
Face : Moderate (Class 3)
Eyelid : Mild (Class 4)
Explanation: Weak potency (class 4) steroids may be used safely for up to 2 weeks even on very thin skinned areas such as eyelids and scrotum. Moderate potency (class 3) may be used for flare-ups on facial skin, but are best avoided long term in these sites. However it is often necessary to used potent (class 2) steroids for thicker skinned areas such as the trunk and limbs and ultrapotent (class 1) steroids for palms and soles.
Which results in enhanced absorption of topical steroid?
#! Ointment base
#! Salicylic acid
# Scaly skin
Which of the following statements are correct?
# 10% of those using ultrapotent topical steroids for one year develop Cushing’s syndrome
#! Potent topical steroids under occlusion may cause cutaneous atrophy
# Perioral dermatitis is usually treated with moderate potency topical steroids
# Intralesional corticosteroids may cause fat hypertrophy
Regarding topical steroids:
# Clobetasol butyrate is more potent than clobetasol propionate
#! Hydrocortisone 17-butyrate is more potent than hydrocortisonee acetate
# Hydrocortisone acetate is more potent than clobetasol butyrate
#! clobetasol propionate is more potent than betamethasone valerate