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Miscellaneous dermatology

Wound healing key points test

Normal wound healing: which of the following statements apply? #! Haemostasis creates a protective wound scab allowing cell migration underneath #! Partial thickness wounds regenerate more rapidly than full thickness wounds # Adult partial thickness wounds heal by regeneration with fibrosis # Fetal full thickness wounds heal by regeneration with fibrosis Explanation: Haemostasis creates a protective wound scab beneath which cell migration and movement of the wound edges can occur. Partial thickness wounds regenerate much more rapidly than full thickness wounds of the same surface area. In adults, full thickness wounds are repaired by fibrosis i.e. a scar. However, fetal wounds heal by regeneration without fibrosis and do not result in scars. # Inflammation prevents wound repair #! Repair includes epithelialization, fibroplasia and capillary proliferation #! An acute wound should show signs of healing in less than 4 weeks # A chronic wound should show signs of healing in less than 4 weeks Explanation: Inflammation brings nutrients to the area of the wound, removes debris and bacteria, and provides chemical stimuli for wound repair. Repair proceeds through the processes of epithelialization, fibroplasia, and capillary proliferation. Acute wounds are expected to show signs of healing in less than 4 weeks. Chronic wounds are those that persist for longer than 4 weeks. Impaired wound healing may arise because of: #! Smoking #! Arterial insufficiency #! Venous insufficiency #! Neuropathy Explanation: Many intrinsic and extrinsic factors can impair wound healing. Arterial insufficiency, venous insufficiency, neuropathy and smoking are among the most important.